do a search on here for "Pre/Pro" or something along those lines.
Basically yes you can, there are a select few folks here you get a good high end audio card with good DACs and use that as their pre/pro instead of an AV reciver or dedicated pre/pro box.
Then from the higher end aduio card (something lke the X-Fi or Maudio pro's) you run your analog out's into the amps.
- Josh