Meedio has an internal player that will handle most file formats. You can install the Playmee plugin for more flexibility. It will allow you to specify which program you want to run files based on any criteria you want (file extension, media library section, etc). I have mine setup to use Zoom Player for movies, the Meedio internal player for Shoutcast streams and mp3's, and it also gets the correct emulator up and running when I select a game rom. You can pass any number of command line arguments to the programs that you want.