The X4000 has more than enough power for that speaker setup and takes the nod on subwoofer EQ using Audyssey MultEQ XT32 which can EQ the subwoofer and also has Audyssey Sub EQ HT (dual sub level/delay calibration) and comes with a 3 year warranty vice only 2 years on the Pioneer. If you plan on connecting a Zone 2, the X4000 can also route an independent HDMI PCM 2.0 signal to Zone 2 and optical/digital coax PCM 2.0 to Zone 3 as well.
hmdi won't go any further then 10 meters unless it has a signal-booster between the cable. some do 15 meters but only thin wire cable will do 1080P on them and no 4k , so it renders zone stuff useless as these signalboosters are expensive. for the 400 u pay more on the denon you could get a nice svs sub and level the bass way better then any audyssey sub eq will be able to do.
Audyssey Sub EQ HT would more likely do a much better job than any manual solution. Also Monoprice 50' cables as well as Redmere 65' cables are both known do work quite well with any additional amplification.
2 good subs would do nicely too. i find any audyssey but pro version lacking and alter the original sound to much, probably me.. 50' will get me as far as the other side of the livingroom... it does 4k ?
but on-topic.. both avr will have enough power to get the klipsch going.. more power will make em sound even better.
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