I've never used a squeezebox, but I believe their UI is more flexibile. The 4306 (and most other receivers) basically let you sort music by ALL, ARTIST, ALBUM, etc., then present you with an alphabetically sorted list to select from. I think you can also set up playlists, haven't played with that feature yet. The 4306 also lets you connect to your PC and play your music over a network connection, as well as Internet Radio access. Not a bad feature package at all, just not a great user interface to go with the features.