My HTPC and AVR are in the basement connected to the TV and speakers on the main floor so I use the XSight Touch remote which is a combination RF/IR remote. It controls the TV via IR but for the HTPC/AVR, it sends an RF signal to the basement where I have the XSight Touch Extender which then blasts the IR signal to the HTPC/AVR. No IR eye needed on the main floor. I'm quite happy with the setup but more importantly, so is my wife.
Edit: I've considered getting a Keyspan RF Media Center remote and seeing if the XSight Touch will work with the Keyspan RF receiver. Haven't done it though since It still wouldn't control the AVR. Maybe when I get an RS-232 capable AVR and can control it with the HTPC.
Edit: I've considered getting a Keyspan RF Media Center remote and seeing if the XSight Touch will work with the Keyspan RF receiver. Haven't done it though since It still wouldn't control the AVR. Maybe when I get an RS-232 capable AVR and can control it with the HTPC.