I just got this set up last night, and it's a fantastic product. Worked flawlessly. After upgrading my iPad to iOS 4.3.5, I was up and running within 10mins.
Plugged in my Global Cache iTach IP2IR into power and to my router, slapped the IR emitters on the front of my receiver and television. Installed the Roomie app from the iTunes AppStore for $9.99, it downloaded the device library, I set up a "Room", added my devices, it detected the IP2IR without a hitch, chose the IR port the emitters were on, chose my devices. Then I set up the "Activities", which are the macros.
Bam, it worked on the first shot, AS EXPECTED, no surprises. The only issues I had were with setting up the timings accordingly with my slow LG television. I set up a few activities (some cool ones like setting it up for my BlackBerry Playbook playback, and my laptop).
I can't wait to push the app a bit more as I dive deeper into lighting controls, and once I'm in the new house with multiple rooms with a centralized AV closet.
So far, Roomie is my dream app, and it's only been out a few days! Well thought out, great UI, simple macro settings, and it's cheap (no need for desktop applications). It doesn't let you customize the look of my buttons, but I don't really care about that anyways.
Try it!