No. Ghost does not understand the Tivo's unique file format.
But you can easily copy and upgrade your current hard drive using the step-by-step instructions at the top of the Tivo Upgrade Center Forum at http://www.tivocommunity.com . As described in the instructions you'll download an .iso file for the Linux-based MFS Tools which you can use to boot your PC and upgrade your Tivo's drive.
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