I use my HTPC as my main desktop. It is easy with modern video cards to connect two monitors (such as a desktop LCD and a projector/plasma TV, etc.), and setup the driver with a hotkey to toggle between them. For Nvidia it is in the Nview desktop manager under the hot keys tab. Under display mode, "switch to next display device".... assign some hotkey combo to it like control-F1.
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Just be sure your video card has two physical connectors, and you should be all set. Mine has a VGA and a DVI (can be VGA with a cheap adapter), for example. Another common configuration is two DVI ports.
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